BioFlex® Overmolded Bottle Stopper Assembly

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BioFlex® Bottle Stopper
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industry experts.
BioFlex® Bottle Stopper
Meissner’s overmolded bottle stopper assembly is available for storage and sampling of media and biological solutions
Meissner’s overmolded bottle stopper assembly is optimized for bottle integration to provide a process solution for applications, such as sampling, that require exposure to a VHP sterilization cycle prior to entering a high classification area for sterility testing and long-term frozen storage of sample product.
Meissner’s overmolded bottle stopper features two 1/8″ inner diameter x ¼” outer diameter tubing lines that provide access to the interior of the bottle. Each of these lines can be specified with dip tubes of various tubing lengths. The tubing, Meissner’s own proprietary M-Flex® thermoplastic elastomer (TPE) tubing offers excellent sealing and welding performance. Meissner’s 25 mm Steridyne® PVDF filter device, or CA2 model filter, provides a sterile vent option on the assembly.
Meissner’s overmolded bottle stopper is manufactured in our ISO Class 7 cleanrooms using the same resin as our M-Flex® TPE tubing and our BioLink® modular overmolding components.
Frequently Asked Questions
What is BioLink® Modular Overmolding Technology?
BioLink® Modular Overmolding Technology is Meissner’s single-use connection platform designed to create secure, modular fluid path connections for biopharmaceutical processing. It combines the strengths of conventional overmolding with the speed and flexibility often associated with mechanical connections, helping users build more robust and adaptable single-use systems. :contentReference[oaicite:1]{index=1}
What is BioLink® used for?
BioLink® is used to connect tubing, filters, and other single-use fluid path components in biopharmaceutical processes. It is designed for applications where secure connectivity, reliable fluid handling, and flexible system design are important. :contentReference[oaicite:2]{index=2}
How does BioLink® Modular Overmolding work?
BioLink® uses two primary components: lengths of M-Flex® TPE tubing with overmolded unitized end-fittings, and polypropylene modules or filter adaptors. These parts are joined using automated welding processes that create permanent thermal bonds with a smooth inner bore. :contentReference[oaicite:3]{index=3}
What are the main benefits of BioLink® technology?
BioLink® is designed to reduce the number of fluid-contact materials, improve process robustness, and provide more secure connectivity to process components such as filters and single-use gauge tees. These benefits can help simplify assembly design and improve reliability in single-use operations. :contentReference[oaicite:4]{index=4}
Why use BioLink® instead of traditional mechanical connections?
BioLink® is designed to provide stronger and more integrated connections than traditional mechanical fittings while still preserving modularity and speed. This can help reduce potential leak points, improve system security, and support more dependable single-use fluid paths. This is an inference based on Meissner’s description of enhanced robustness and secure connectivity. :contentReference[oaicite:5]{index=5}
What tubing sizes does BioLink® support?
BioLink® is shown as compatible with multiple M-Flex® tubing sizes, including 1/8 inch ID x 1/4 inch OD, 1/4 inch ID x 7/16 inch OD, 3/8 inch ID x 5/8 inch OD, and 1/2 inch ID x 3/4 inch OD. The page also states that any size tubing can be adapted to any module or filter. :contentReference[oaicite:6]{index=6}
What connection types are available with BioLink®?
BioLink® supports multiple connection formats, including union modules, single bifurcation modules, dual bifurcation modules, and direct connectivity to filters. This gives users flexibility when designing single-use assemblies for different process layouts. :contentReference[oaicite:7]{index=7}
How does BioLink® integrate with filters and other Meissner components?
BioLink® is specifically designed to enhance secure connectivity to processing steps such as filters and SGTs, or single-use gauge tees. It also uses polypropylene modules and filter adaptors molded from the same resin used across much of Meissner’s filter portfolio, supporting material consistency across the system. :contentReference[oaicite:8]{index=8}
Why is the smooth inner bore important in BioLink® connections?
A smooth inner bore helps support cleaner fluid flow through the connection path and can reduce turbulence, hold-up, or disruption at connection points. This is an inference based on the page’s note that automated welding creates permanent thermal bonds with a smooth inner bore. :contentReference[oaicite:9]{index=9}
Is BioLink® suitable for biopharmaceutical single-use systems?
Yes. BioLink® is presented by Meissner as part of its single-use systems portfolio and is designed for biopharmaceutical fluid path applications that require secure, modular, and process-robust connectivity. :contentReference[oaicite:10]{index=10}