Tangential Flow Capsule Filters

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SepraPor® Capsules
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SepraPor® Capsules
SepraPor® Microporous Hollow Fiber Capsule Filters
SepraPor® tangential flow filtration capsules are available in a range of configurations to seamlessly scale from lab applications to full-scale production, with effective filtration areas (EFA) from 0.011 m2 to 4.4 m2. The capsules are available as a standalone filter or as part of a process-ready, gamma-sterilized assembly. Microporous SepraPor® capsules are available in porosity ratings of 0.1 µm, 0.2 µm, and 0.4 µm.
Which SepraPor® Tangential Flow Filter Should You Use?
Our interactive Shear Rate Calculator tool will calculate the shear rate for a given filter diameter and recirculation (volumetric flow) rate to help you determine the optimal SepraPor® filter size for your application.
SepraPor® Hollow Fiber Capsule Filter 360° View

4 1/2 Inch Hollow Fiber Capsule Filter

3/8 Inch Hollow Fiber Capsule Filter
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Frequently Asked Questions
What are Tangential Flow Capsule Filters?
Tangential Flow Capsule Filters by Meissner Corporation are ready-to-use, disposable filter assemblies designed for critical point-of-use filtration and small batch processing of liquids and gases. They feature a compact polypropylene housing with a thermally bonded filter element, ensuring no bypass and high filtration reliability. These filters comply with FDA food contact standards and USP Class VI biological reactivity tests, making them suitable for various applications requiring contamination control.
What applications are Tangential Flow Capsule Filters used for?
Tangential Flow Capsule Filters are used in pharmaceutical, biological, bioprocessing, electronics, chemical, food and beverage, and cosmetics industries. They control particulate and microbial contamination in liquid and gas applications, suitable for point-of-use and small to medium batch processing. These filters are ideal for laboratory, pilot plant, and production settings with flow rates less than 3 gpm (11 L/min) or 25 cfm (42.5 m³/hr).
What specifications or sizes are available for Tangential Flow Capsule Filters?
Meissner Tangential Flow Capsule Filters come in several sizes with nominal diameters ranging from 1.25″ to 2.75″ and lengths from 3.25″ to 10″. Models include CF(2), CS(2), CL(2), CJ2, CM2, and CK2. Operating temperature ranges are typically 0°C to 38°C or up to 50°C depending on model, with maximum operating pressures up to 100 psig (6.9 bar) at 122°F (50°C) for liquids and gases. They feature polypropylene housings and support components with thermal bonding sealing.
What makes Tangential Flow Capsule Filters unique?
Tangential Flow Capsule Filters feature a permanently sealed, one-piece polypropylene housing thermally bonded to the filter element, eliminating bypass risk and ensuring filtration integrity. They meet stringent FDA and USP Class VI standards without using binders or adhesives, resulting in biosafe, non-fiber-releasing filters. Their compact design, multiple membrane options, and compatibility with autoclaving and gamma irradiation (up to 40 kGy for certain membranes) provide high reliability, chemical resistance, and user convenience.
Are Tangential Flow Capsule Filters suitable for regulated biopharmaceutical manufacturing?
Yes, Tangential Flow Capsule Filters are suitable for regulated biopharmaceutical manufacturing. They are manufactured in conformance with cGMP, comply with FDA food contact regulations (21 CFR 177), meet USP Class VI plastics biological reactivity tests, and are non-fiber-releasing per 21 CFR 210.3(b)(6) and 211.72. Their validated manufacturing and quality control processes ensure product performance and traceability required for regulated environments.
What other products are commonly used with Tangential Flow Capsule Filters?
Common complementary products used with Tangential Flow Capsule Filters include Single-Use Systems, M-Flex® TPE Tubing, M-Sil™ Braid Reinforced Silicone Tubing, BioLink® Modular Overmolding Technology, and BioFlex® Fluid Path Assemblies. These products support fluid handling and system integration in bioprocess workflows.
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