TepoFlex® PE Biocontainers

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TepoFlex®

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Polyethylene-based (PE) biocontainers optimized for single-use system requirements within the biopharmaceutical industry

Within Meissner’s One-Touch® portfolio of single-use systems, TepoFlex® PE biocontainers provide robust, secure fluid handling options. TepoFlex® PE biocontainers are available in standard sizes in 2D end-ported designs (from 50 mL to 20 L), face-ported 2D designs (from 5 L to 200 L), and 3D designs (from 100 L to 1,000 L). Custom biocontainer assemblies in 1,000 L+ for customer-specific requirements can be designed by our Applications Engineering Team. TepoFlex® can be fitted with customer-specified tubing lengths, connectors, and end fittings, or ordered with BioFlex® fluid path/tubing assemblies to provide maximum flexibility. Custom biocontainers can be designed to meet the requirements of customers’ existing rigid outer containers and bioprocessing systems. Specialty biocontainers, such as the FlexFill® transfer assembly, can provide maximum ease and convenience for aseptic transfer of small process volumes, while FlexGro® rocker style assemblies are ideal for cell culture applications. A TepoFlex® PE biocontainer ‘standards’ design library, which we call our Standards Guide, provides end users with quick, convenient options for most common fluid handling applications.

Meissner has engineered slip agents out of the TepoFlex® manufacturing process, so they can’t leach into your process fluids. Our innovative welding technology maintains 95% of the film’s strength to provide outstanding security for your process fluids. TepoFlex® PE biocontainers and fluid path assemblies are backed by a comprehensive qualification guide to support end users. FlexStation® rigid outer shipping and storage containers fit Meissner’s TepoFlex® 3D biocontainers to provide shipping and storage solutions. Our QuaDrum® containers offer an alternative to cylindrical drum containers and securely support TepoFlex® 3D biocontainers for intrafacility storage needs.

Frequently Asked Questions

What are TepoFlex® PE Biocontainers?

TepoFlex® PE Biocontainers are polyethylene-based single-use biocontainers designed for secure fluid handling in biopharmaceutical processes. As part of Meissner’s One-Touch® single-use portfolio, they are built to support low extractables, strong film performance, and flexible integration across a wide range of process applications.

What are TepoFlex® biocontainers used for?

TepoFlex® biocontainers are used for storage, transfer, mixing, and handling of process fluids in biopharmaceutical and other high-purity applications. They are designed for single-use workflows where fluid integrity, low extractables, and operational flexibility are important.

What sizes and configurations are available for TepoFlex® biocontainers?

TepoFlex® biocontainers are available in a wide range of 2D and 3D configurations, from small laboratory and process development volumes to large production-scale formats. Standard options include end-ported and face-ported 2D designs, larger 3D assemblies, and specialty configurations for transfer and cell culture applications.

What are slip agents in biocontainer films?

Slip agents are additives used in some polymer films to increase surface lubricity and help the film slide more easily over itself. While they can improve handling during film processing, they may also contribute to leachables, reduce film clarity, and affect sealing performance in critical single-use applications.

Why does TepoFlex® film not use slip agents?

TepoFlex® film is designed without slip agents to help reduce a potential source of leachable compounds and support higher film clarity and stronger seal performance. This can be especially important in biopharmaceutical processes where product compatibility, purity, and long-term fluid integrity matter.

What makes the TepoFlex® welding technology important?

TepoFlex® biocontainers use welding technology designed to preserve a high percentage of the original film strength across welded areas. This helps improve assembly durability, supports fluid security during handling, and reduces the risk of leaks or failures in demanding process conditions.

Can TepoFlex® biocontainers be customized?

Yes. TepoFlex® biocontainers can be customized with different tubing lengths, connectors, end fittings, and integrated assembly options. Custom configurations can also be developed to fit specific process equipment, rigid outer containers, or broader single-use system requirements.

What specialty TepoFlex® assemblies are available?

Specialty TepoFlex® assemblies include configurations designed for aseptic transfer and cell culture applications, such as transfer-focused assemblies and rocker-style formats. These options help users match the biocontainer design to specific process steps and operational needs.

How do TepoFlex® biocontainers integrate with other systems?

TepoFlex® biocontainers are designed to integrate with Meissner’s broader single-use portfolio, including fluid path assemblies and support hardware. They can also be configured for compatibility with rigid outer containers and custom process setups, which helps users build more complete single-use workflows.

Are TepoFlex® biocontainers supported by qualification documentation?

Yes. TepoFlex® biocontainers are supported by qualification and standards documentation to help users evaluate the assemblies for common fluid-handling applications. This documentation can help streamline product selection, validation, and implementation in regulated process environments.

Why choose TepoFlex® PE over standard PE biocontainers?

TepoFlex® PE biocontainers are designed to offer advantages in film purity, low extractables, seal performance, and customization flexibility. Their slip-agent-free film platform and high-strength welded construction make them well suited for critical biopharmaceutical applications where process security and product compatibility are essential.

Biocontainer Shapes & Sizes


2D End-ported 50 mL – 20 L
2D End-ported 50 mL – 20 L
3D Top & Bottom-Ported for FlexStation® 100 L – 1,000 L
3D Top & Bottom-Ported for FlexStation® 100 L – 1,000 L
3D Top-ported for QuaDrum® 25 L – 200 L
3D Top-ported for QuaDrum® 25 L – 200 L
3D Top-Ported for FlexStation® 100 L – 1,000 L
3D Top-Ported for FlexStation® 100 L – 1,000 L
FlexFill® 500 mL – 6 L+
FlexFill® 500 mL – 6 L+

TepoFlex® Biocontainer 360° View


Universal Lab Stand With TepoFlex PE End-Ported Biocontainer and Filter

Universal Lab Stand With TepoFlex® PE End-Ported Biocontainer and Filter

Universal Lab Stand with TepoFlex PE Biocontainer

Universal Lab Stand With TepoFlex® PE End-Ported Biocontainer

TepoFlex® PE Biocontainer Videos


Citations


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TepoFlex®

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