Saltus® CFD Study
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CFD Study
Let's talk.
Send a message to our
industry experts.
CFD Study
An in-depth analysis of the Saltus® Single-Use Mixer’s capabilities
Meissner has conducted a thorough Computational Fluid Dynamics (CFD) study in support of the Saltus® M200 Next Generation Single-Use Mixing System. The data gathered illustrates the Saltus® M200’s performance characteristics and highly effective mixing capabilities.
Homogenization 6 Hz – Dual Oscillation
The CFD study reliably predicts the operational performance of our Saltus® M200. While the high frequency, low amplitude agitation vibromixing technology employed by the Saltus® is a well-established technology, its implementation into a next generation single-use mixing platform is unique. This CFD study provides end-users with an understanding of the system’s mixing dynamics as well as valuable information, such as shear stress imparted to the fluid during mixing.
Characterization of both fluid flow as well as sheer stress was performed, and homogenization performance was analyzed. The resulting data generated allows for easy comparison of agitator configuration alternatives in conjunction with various process settings, in order to assist clients in selecting the best option for their mixing applications. Video data of various mixing scenarios graphically depicts the mixer’s effectiveness over elapsed time and can be accessed below.
The extensive CFD study analysis was performed on the Saltus® M200 mixing system for the following parameters:
- Single and dual disc agitator configurations
- Fluid fill volumes ranging from 50 L to 200 L
- Multiple agitation frequencies spanning the range of typical operation
To evaluate the fluid flow, shear stress, and homogenization performance of the Saltus® M200 mixing system, models were generated to develop velocity vector diagrams, sheer stress analyses, and mass fraction method homogenization scenarios. The results demonstrate that the Saltus® M200 mixer is unique in its capability to provide exceptionally fast homogenization performance while delivering a low shear, gentle mixing profile that promotes a high level of mass fluid flow.
For more in depth information on the contents of the CFD study, please contact Meissner directly.
CFD Study Analysis Videos
Frequently Asked Questions
What is Saltus® CFD Study?
Saltus® CFD Study is a detailed Computational Fluid Dynamics (CFD) analysis of the Saltus® Single-Use Mixer. It evaluates fluid flow patterns, mixing efficiency, and shear conditions within the mixer to optimize performance in biopharmaceutical processes.
What applications is Saltus® CFD Study used for?
Saltus® CFD Study is used to assess and optimize mixing performance in single-use bioprocessing applications, including cell culture, buffer preparation, and formulation. It supports process development by simulating fluid dynamics to ensure homogeneity and minimize shear stress.
What specifications or sizes are available for Saltus® CFD Study?
Saltus® CFD Study does not have physical size specifications as it is a simulation service. It analyzes the Saltus® Single-Use Mixer across various operational volumes and configurations to provide tailored fluid dynamic insights.
What makes Saltus® CFD Study unique?
Saltus® CFD Study offers an in-depth, application-specific fluid dynamic analysis of the Saltus® Single-Use Mixer, enabling precise optimization of mixing parameters. It uses advanced CFD modeling techniques to predict flow behavior and mixing efficiency under different process conditions.
How does Saltus® CFD Study integrate with other systems?
Saltus® CFD Study integrates by providing fluid dynamic data that informs the design and operation of the Saltus® Single-Use Mixer within broader bioprocess systems. The study supports system integration by optimizing mixer performance to match upstream and downstream process requirements.
Is Saltus® CFD Study suitable for regulated biopharmaceutical manufacturing?
Saltus® CFD Study supports regulated biopharmaceutical manufacturing by providing validated fluid dynamic analyses that help ensure consistent and reproducible mixing performance. The study aids in process characterization and validation efforts compliant with industry standards.
Can Saltus® CFD Study be customized?
Yes, Saltus® CFD Study can be customized to simulate specific process conditions, mixer configurations, and fluid properties. Customization enables targeted analysis to address unique mixing challenges and optimize performance for individual bioprocess applications.
What other products are commonly used with Saltus® CFD Study?
Saltus® CFD Study is commonly used alongside complementary downstream products such as Single-Use Systems, M-Flex® TPE Tubing, BioFlex® Fluid Path Assemblies, and Universal Lab Stand. These products support fluid transfer, containment, and system support in bioprocess workflows.
