Single-use systems are disposable or single-use fluid handling systems used in biopharmaceutical processing to transfer, store, mix, sample, filter, and manage process fluids. A single-use system can include biocontainers, tubing, connectors, filters, sensors, mixing components, and other integrated fluid path components. Unlike traditional stainless-steel process equipment, single-use systems are designed for one processing campaign and are typically supplied ready for deployment.

Meissner One-Touch® single-use systems are integrated fluid handling solutions designed for biopharmaceutical processing. The portfolio includes single-use biocontainers, fluid path assemblies, mixing and transfer assemblies, support hardware, and monitoring components that help support fluid transfer, storage, mixing, and scalable bioprocess operations from research and process development through production.

Single-use systems are used for a wide range of bioprocessing applications, including fluid transfer, media and buffer storage, mixing, sampling, filling, shipping, and other critical process operations. They can be used throughout upstream and downstream biopharmaceutical workflows where controlled fluid handling, sterility, flexibility, and efficient deployment are important.

A single-use system can combine multiple components into an integrated fluid path. Common components include biocontainers, tubing, connectors, filters, valves, pressure monitoring devices, mixing assemblies, transfer assemblies, and support hardware. Meissner’s One-Touch® portfolio provides single-use components and assemblies designed to work together as part of complete fluid handling systems.

Single-use systems can simplify bioprocess operations by reducing or eliminating many of the cleaning and sterilization activities associated with reusable stainless-steel equipment. They can also support faster deployment, reduce cross-contamination concerns between campaigns, simplify process changeover, and provide flexibility when scaling or modifying a process. The specific benefits depend on the application, system design, materials, and operating requirements.

Single-use systems use disposable components such as biocontainers, tubing, and fluid path assemblies, while traditional systems commonly rely on reusable stainless-steel equipment. Single-use technology can reduce cleaning, sterilization, and changeover requirements and can make smaller or changing production processes easier to deploy. Stainless-steel systems remain widely used for applications where long-term equipment reuse, large-scale processing, or other process requirements make reusable equipment appropriate.

Single-use biocontainers are flexible containers used to store, transport, mix, or process biopharmaceutical fluids. They are typically manufactured from polymeric films and can be configured with tubing, connectors, ports, and other components to create an integrated single-use fluid path. Meissner offers TepoFlex® polyolefin-based biocontainers in 2D and 3D configurations for different processing and storage requirements.

The One-Touch® portfolio includes TepoFlex® polyolefin-based biocontainers in both 2D and 3D formats, along with FlexFill® biocontainer transfer assemblies and FlexFill® mixing assemblies. These options support a range of single-use processing, storage, transfer, and mixing applications across multiple scales.

2D biocontainers are typically used for lower-volume applications and are designed for flexible handling and compact storage. 3D biocontainers are generally used for larger-volume applications and can be deployed in rigid support containers that help maintain bag shape and provide stability during storage, handling, and transport. Learn more about TepoFlex® PE Biocontainers.

Single-use fluid path assemblies connect the components used to move and manage process fluids within a bioprocess. They can include tubing, connectors, filters, valves, sensors, and other components configured for a specific application. Meissner BioFlex® fluid path assemblies provide configurable single-use tubing and connection solutions designed for fluid transfer within bioprocess workflows.

BioFlex® fluid path assemblies are single-use tubing and connection assemblies designed to provide flexible fluid transfer within bioprocess workflows. They can be configured to support different process requirements and can integrate with Meissner single-use systems as well as compatible traditional process equipment.

FlexStation® rigid outer containers provide structural support for TepoFlex® 3D biocontainers during storage, handling, and transport. They help manage filled biocontainers in larger-volume single-use applications and can be paired with carts or pallet trucks for easier movement of deployed assemblies.

QuaDrum® containers provide a rigid support option for deployment and storage of Meissner single-use biocontainer assemblies. They are designed to help users manage filled systems during bioprocessing, storage, handling, and transportation.

FlexCessory™ support products are accessories designed to complement Meissner single-use systems. They provide practical hardware for setup, operation, handling, and support of single-use assemblies throughout bioprocess workflows.

The SGT Single-Use Gauge Tee is a pre-sterilized single-use component designed for in-line pressure monitoring. It allows users to monitor process pressure within a fluid path while maintaining the integrity of the single-use system.

BioLink® modular overmolding technology is Meissner’s approach to creating integrated single-use connections. Built around M-Flex® TPE tubing, BioLink® is designed to integrate components such as filters and pressure monitoring devices into single-use fluid paths while supporting consistent assembly and connection.

Single-use systems can be used across many stages of biopharmaceutical manufacturing, including upstream processing, downstream processing, media and buffer preparation, fluid transfer, storage, mixing, filtration, sampling, filling, and shipping. They are used in applications ranging from process development and clinical manufacturing to commercial production. Meissner’s One-Touch® portfolio provides single-use solutions for many of these fluid handling applications.

Yes. Single-use systems can support both upstream and downstream bioprocessing operations. Depending on the process, applications can include media and buffer storage, fluid transfer, mixing, sampling, filtration, intermediate storage, and other fluid handling operations. Meissner provides single-use systems and components designed for use across multiple stages of biopharmaceutical processing.

Meissner single-use systems are designed to support controlled fluid handling, operational efficiency, and scalable process design. The One-Touch® portfolio combines biocontainers, fluid path assemblies, mixing and transfer solutions, support hardware, and monitoring components to help users configure integrated single-use systems for biopharmaceutical workflows.